Illustration

Blood Orange

Blood Orange CLIENT Norman Barker YEAR 2023 MEDIA Photography, Adobe Photoshop DESCRIPTION This poster was created as a photography exercise. It describes the basic anatomy, cultural history, and science behind the vibrant color of a blood orange.

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Composing Proteins

Composing Proteins CLIENT Jennifer Fairman, Tim Phelps YEAR 2023 MEDIA Adobe Photoshop, Procreate DESCRIPTION This illustration was created as a mock journal cover. It is based on an article about a research team using an algorithm based on classical music to read protein structures and turn them into sound.

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Popliteal Artery Bypass

Popliteal Artery Bypass CLIENT Corinne Sandone, Tim Phelps YEAR 2023 MEDIA Adobe Photoshop, Procreate DESCRIPTION This illustration depicts a key surgical moment from an open popliteal bypass surgery. This procedure used a harvested great saphenous vein graft to bypass an aneurysm in the popliteal artery. Didactic color was used to clearly identify the graft and artery across figures. Figure A depicts the below-knee arteriotomy. In Figure B, the graft is packed to the arteriotomy and suturing begins. Figure C depicts the suturing near-completion and in the context of the below-knee incision. The illustration was created for journal format. Surgical Sketches I created sketches of the entire procedure based on my experience observing the surgery in the operating room.

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Antibiotic Resistance

Antibiotic Resistance, Livestock, and You CLIENT Jeff Day, Jennifer Fairman YEAR 2022 MEDIA Adobe Illustrator, Tableau DESCRIPTION This piece describes the way antibiotic use in animal agriculture contributes to antibiotic resistance for an educated lay audience. The main image illustrates the pathway of bacteria to consumers. Insets visualize United States data about antibiotic use and foodborne illness from resistant bacteria.

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Husbandry Considerations for Choloepus Senses

Husbandry Considerations for Choloepus Senses CLIENT National Aquarium, Jeff Day, Tim Phelps YEAR 2023 MEDIA Procreate, Adobe Photoshop DESCRIPTION Two-toed sloths (Choloepus) have limited vision and hearing, which informs the way human caretakers interact with them. Created in collaboration with the National Aquarium, this poster describes Choloepus vision and hearing for an audience of people involved in sloth husbandry and an informed lay audience. The top illustration shows the rarely-illustrated eye anatomy of a sloth, depicted in the orbit. An inset compares models of full color vision and Choloepus vision. Two sloth portraits contextualize the orbit and external ear. The bottom banner describes best practices for sloth caretakers.

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Deep Structures of the Telencephalon

Deep Structures of the Telencephalon CLIENT Lydia Gregg, Mary Ann Wilson YEAR 2023 MEDIA Graphite, Adobe Photoshop DESCRIPTION This illustration was developed as part of a dissection guide to clarify the position of deep brain structures, which are partially visible at the end of the dissection. First, an L-shaped inset provides a step-by-step guide to access the deep structures of the diencephalon. To depict the position of each cut, three-dimensional colored boxes highlight the cortex and white matter removed in each step. External anatomy and cortical regions are highlighted as they are encountered in dissection. The main illustration depicts the anatomic relationships between the deep periventricular structures of the telencephalon in the final stage of the dissection. The overlying cortex, caudate nucleus, thalamus, and amygdala were rendered as partially transparent to clarify the position of these structures and show the arrangement of the hippocampus and fornix. Didactic color was used to help students visualize the position of these structures.

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Cholecystectomy

Robot-assisted Cholecystectomy CLIENT Corinne Sandone, Jennifer Fairman YEAR 2023 MEDIA Adobe Photoshop, Procreate DESCRIPTION This illustration depicts a key surgical moment from a robot-assisted cholecystectomy. In this procedure, the cystic duct and cystic artery are clipped and divided in order to remove the gallbladder. Figure 4a shows the critical view of safety, where the gallbladder has been partially mobilized and the surface of the liver is visible between the cystic duct and artery. Observation of the critical view of safety prevents accidental clipping of the surrounding biliary tree and arteries, which are ghosted in. Figure 4b shows the subsequent division of the cystic duct and artery. This piece was designed for slide format. Surgical Sketches I created sketches of the entire procedure based on my experience observing the surgery in the operating room.

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Engineering Immunocytokines

Engineering immunocytokines to promote anti-tumor activity CLIENT Fabian de Kok-Mercado, Lydia Gregg, Jamie Spangler YEAR 2023 MEDIA PyMOL, Cinema 4D, Adobe Photoshop DESCRIPTION The engineered F10 immunocytokine is composed of an F10 antibody linked to interleukin-2 (IL-2). The structure of the immunocytokine favors the binding of IL-2 to the IL-2 receptor heterodimer on e ector T cells, which triggers a pathway that promotes antitumor activity. This illustration depicts this interaction in an immersive tumor cell environment. The illustration was created for a journal cover, and molecule colors were chosen to align with the accompanying paper’s figure legend. The anatomy of the immunocytokine is labeled, as well as the beta and gamma subunits of the IL-2 receptor. The secondary structure of the subunits, a highlight of the accompanying paper, are included in the illustration. An inset shows a zoomed-out view of an e ector T cell on a tumor cell to contextualize the main image.

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The Optic Nerve Head

The Optic Nerve Head CLIENT Lydia Gregg, Ian Pitha YEAR 2023 MEDIA Graphite, Adobe Photoshop DESCRIPTION This illustration depicts the anatomy of the optic nerve head as it pertains to normal function and glaucoma. First, the main image’s view and orientation are introduced by the inset in the top left. In the main image, a wedge-shaped section of the eye has been removed to show the anatomic relationships between the optic nerve axons, lamina cribrosa, and peripapillary sclera. The section view is offset to reveal the path of the central retinal vessels. To the right of the main image, insets describe the pathology of glaucoma. The top right inset depicts excavation of the optic nerve head. Graphic cellular depictions at the bottom right show the distribution of fibroblasts and glial cells within the nerve axons and extracellular tissue before and after glaucoma, highlighting the extensive cell death seen with excavation.

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